Genes

CXCR4

Chemokine (C-X-C motif) receptor 4 (CXCR4) is a gene that encodes a protein that functions as a chemokine receptor that is specific for stromal cell-derived factor 1. The protein, along with the CD4 protein, supports HIV entry into cells. Missense mutations, nonsense mutations, silent mutations, and frameshift deletions are observed in cancers such as intestinal cancer, lung cancer, and skin cancer.

Modified: July 1, 2015

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