Genes

CLTC

Clathrin, heavy chain (Hc) (CLTC) is a gene that encodes a protein that functions as a component of the cytoplasmic face of intracellular organelles (coated vesicles and coated pits). The organelles are important for the intracellular trafficking of receptors and the endocytosis of macromolecules. Fusions, missense mutations, nonsense mutations, silent mutations are observed in cancers such as breast cancer, intestinal cancer, and ovarian cancer.

Modified: July 1, 2015

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