Cleavage and polyadenylation factor I subunit 1 (CLP1) is a gene that encodes a protein that is a multifunctional kinase that is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex. Fusions, missense mutations, nonsense mutations, and silent mutations are observed in cancers such as bone cancer, intestinal cancer, and skin cancer.

Modified: July 1, 2015

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