Class II, major histocompatibility complex, transactivator (CIITA) is a gene that encodes a protein that functions as a positive regulator of class II major histocompatibility complex gene transcription. The protein also facilitates its own transport into the nucleus by binding GTP. Fusions, missense, nonsense, and silent mutations are observed in cancers such as cancers of the central nervous system, intestinal cancer, and skin cancer.

Modified: July 1, 2015

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