Genes

CHEK1

Checkpoint kinase 1 (CHEK1) is a gene that encodes a protein that is a member of the serine/threonine kinase family. The protein functions in the cell cycle arrest response to DNA damage or unreplicated DNA. Missense mutations, nonsense mutations, silent mutations, and frameshift deletions and insertions are observed in cancers such as endometrial cancer, intestinal cancer, and stomach cancer.

Related Pathways

Modified: December 4, 2015

Disclaimer: The information presented at padiracinnovation.org is compiled from sources believed to be reliable. Extensive efforts have been made to make this information as accurate and as up-to-date as possible. However, the accuracy and completeness of this information cannot be guaranteed. Despite our best efforts, this information may contain typographical errors and omissions. The contents are to be used only as a guide, and health care providers should employ sound clinical judgment in interpreting this information for individual patient care.