Chromodomain helicase DNA binding protein 4 (CHD4) is a gene that encodes a protein that is the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Missense mutations, synonymous mutations, nonsense mutations, inframe deletions, frameshift deletions, and frameshift insertions are observed in cancers such as stomach cancer, endometrial cancer, and colon cancer.

Modified: January 7, 2016

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