Caudal type homeobox 2 (CDX2) is a gene
that encodes a transcription factor protein that regulates intestine specific
genes involved in cell growth and
differentiation. The protein is also involved
in embryonic development of the intestinal tract. Fusions, missense mutations, nonsense mutations,
silent mutations, and frameshift deletions are
observed in cancers such as endometrial cancer, intestinal cancer, and stomach cancer.
July 1, 2015
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