Genes

CDKN1A

Cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A) is a gene that encodes a protein that functions as a potent cyclin-dependent kinase inhibitor. The protein inhibits cyclin/CDK2 or cyclin/CDK4 complexes. Missense mutations, nonsense mutations, silent mutations, and frameshift deletions and insertions are observed in cancers such as intestinal cancer, liver cancer, and stomach cancer.

Modified: July 1, 2015

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