Cyclin-dependent kinase 2 (CDK2) is a
gene that encodes a member of the serine/threonine protein kinase family that functions in cell
cycle regulation. Specifically, the protein is important for the progression from G1 to S phase.
Missense mutations, silent mutations, and frameshift deletions are observed in cancers such as
endometrial cancer, skin cancer, and stomach cancer.
December 4, 2015
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