Core-binding factor, run domain, alpha subunit 2; translocated to, 3 (CBFA2T3) is a gene that encodes a protein that belongs to the myeloid translocation gene family. The protein interacts with DNA-bound transcription factors and recruits corepressors to participate in transcriptional repression. Fusions, rearrangements, missense mutations, nonsense mutations, silent mutations, and frameshift deletions and insertions are observed in cancers such as intestinal cancer, skin cancer, and stomach cancer.

Modified: July 1, 2015

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