BH3 interacting domain death agonist (BID) is a gene that encodes a protein that functions as a death agonist that heterodimerizes with BAX (agonist) or BCL2 (antagonist). The protein mediates mitochondrial damage prompted by caspase 8. Missense mutations and silent mutations are observed in cancers such as intestinal cancer.

Related Pathways

Modified: December 4, 2015

Disclaimer: The information presented at is compiled from sources believed to be reliable. Extensive efforts have been made to make this information as accurate and as up-to-date as possible. However, the accuracy and completeness of this information cannot be guaranteed. Despite our best efforts, this information may contain typographical errors and omissions. The contents are to be used only as a guide, and health care providers should employ sound clinical judgment in interpreting this information for individual patient care.