BCL6 corepressor (BCOR) is a gene that encodes a protein of the same name. BCOR is a member of the ankyrin repeat
domain containing gene family. The corepressor
expressed by BCOR binds to BCL6, a DNA-binding protein
that acts as a transcription repressor for
genes involved in regulation of B cells, a
type of immune cell (Gene 2014a, 2014b; Genetics Home Reference 2014).
In cancer, BCOR mutations have been observed in myelodysplastic syndromes, endometrial cancer,
and other cancers.
Strickland, S.A., Kim, A.S. 2014.
My Cancer Genome
(Updated September 2014)
September 23, 2014
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