Genes

BCOR

BCL6 corepressor (BCOR) is a gene that encodes a protein of the same name. BCOR is a member of the ankyrin repeat domain containing gene family. The corepressor expressed by BCOR binds to BCL6, a DNA-binding protein that acts as a transcription repressor for genes involved in regulation of B cells, a type of immune cell (Gene 2014a, 2014b; Genetics Home Reference 2014). In cancer, BCOR mutations have been observed in myelodysplastic syndromes, endometrial cancer, and other cancers.​

Contributors: Stephen A. Strickland, M.D., MSCI, Annette S. Kim, M.D., Ph.D.

Suggested Citation: Strickland, S.A., Kim, A.S. 2014. BCOR. My Cancer Genome https://www.padiracinnovation.org/content/gene/bcor/ (Updated September 2014)

Modified: September 23, 2014

Disclaimer: The information presented at padiracinnovation.org is compiled from sources believed to be reliable. Extensive efforts have been made to make this information as accurate and as up-to-date as possible. However, the accuracy and completeness of this information cannot be guaranteed. Despite our best efforts, this information may contain typographical errors and omissions. The contents are to be used only as a guide, and health care providers should employ sound clinical judgment in interpreting this information for individual patient care.