BRCA associated protein-1 (ubiquitin carboxy-terminal hydrolase) (BAP1) is a gene that encodes a protein that has a high affinity for the BRCA1 protein and functions as a tumor suppressor
protein. Missense mutations, nonsense mutations,
silent mutations, frameshift insertions and
deletions, and in-frame insertions and deletions are observed in cancers such as biliary tract
cancers, eye cancers, and pleura cancers.
July 1, 2015
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