Additional sex combs like transcriptional regulator 1 (official symbol ASXL1) is a gene that codes for a chromatin-binding
protein. Normal ASXL1 plays a role in
embryonic development (Gene 2014). ASXL1 mutations are observed
primarily in myelodysplastic syndromes, but they are also observed in colorectal and
endometrial cancers (COSMIC).
Strickland, S.A., Kim, A.S. 2015.
My Cancer Genome
(Updated December 2015)
December 4, 2015
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