The scientists here included studies reporting the MMSE in patients with dementia or MCI one year prior to the beginning of the COVID-19 pandemic and one year after the lockdown. Patients with dementia exhibited significant MMSE decline compared to pre-pandemic levels. Sub-analyses of dementia types also indicated cognitive decline during lockdown, and a 12-month follow-up revealed an MMSE decline among dementia patients. During the COVID-19 lockdown, there was an overall decline in MMSE scores amongst those with dementia or MCI when compared to pre-pandemic parameters.
